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Cardioprotective Effects of Combined Therapy with Hyperbaric Oxygen and Diltiazem Pretreatment on Myocardial Ischemia-Reperfusion Injury in Rats

Background/Aims: In this study, we examined whether the combination of hyperbaric oxygen (HBO) and diltiazem therapy provided a cardioprotective effect on myocardial ischemia-reperfusion injury (MIRI) rat model. Methods: Sixty healthy Sprague-Dawley rats were randomly divided into sham, IR, diltiaze...

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Principais autores: Chunxia Chen, Wan Chen, Zhihuan Nong, Yuan Ma, Shaoling Qiu, Guangwei Wu
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2016-05-01
coleção:Cellular Physiology and Biochemistry
Assuntos:
Hyperbaric oxygen
Diltiazem
Myocardial ischemia-reperfusion injury
Nitric oxide
Apoptosis
Acesso em linha:http://www.karger.com/Article/FullText/445561
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