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Rad6-Bre1-mediated histone H2B ubiquitylation modulates the formation of double-strand breaks during meiosis
An E2 ubiquitin-conjugating enzyme, Rad6, working with an E3 ubiquitin ligase Bre1, catalyzes monoubiquitylation of histone H2B on a C-terminal lysine residue. The rad6 mutant of Saccharomyces cerevisiae shows a meiotic prophase arrest. Here, we analyzed meiotic defects of a rad6 null mutant of budd...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC509210/ https://ncbi.nlm.nih.gov/pubmed/15280549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400078101 |
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