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Rad6-Bre1-mediated histone H2B ubiquitylation modulates the formation of double-strand breaks during meiosis

An E2 ubiquitin-conjugating enzyme, Rad6, working with an E3 ubiquitin ligase Bre1, catalyzes monoubiquitylation of histone H2B on a C-terminal lysine residue. The rad6 mutant of Saccharomyces cerevisiae shows a meiotic prophase arrest. Here, we analyzed meiotic defects of a rad6 null mutant of budd...

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Sonraí Bibleagrafaíochta
Main Authors: Yamashita, Kentaro, Shinohara, Miki, Shinohara, Akira
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2004
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC509210/
https://ncbi.nlm.nih.gov/pubmed/15280549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400078101
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