Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

A major hallmark of the autoimmune demyelinating disease multiple sclerosis (MS) is immune cell infiltration into the brain and spinal cord resulting in myelin destruction, which not only slows conduction of nerve impulses, but causes axonal injury resulting in motor and cognitive decline. Current t...

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Evonuk, Kirsten S., Moseley, Carson E., Doyle, Ryan E., Weaver, Casey T., DeSilva, Tara M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2016
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5092010/
https://ncbi.nlm.nih.gov/pubmed/27685467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54348
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