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Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

A major hallmark of the autoimmune demyelinating disease multiple sclerosis (MS) is immune cell infiltration into the brain and spinal cord resulting in myelin destruction, which not only slows conduction of nerve impulses, but causes axonal injury resulting in motor and cognitive decline. Current t...

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Библиографические подробности
Опубликовано в: :J Vis Exp
Главные авторы: Evonuk, Kirsten S., Moseley, Carson E., Doyle, Ryan E., Weaver, Casey T., DeSilva, Tara M.
Формат: Artigo
Язык:Inglês
Опубликовано: MyJove Corporation 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5092010/
https://ncbi.nlm.nih.gov/pubmed/27685467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54348
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