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Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry

Methylation of cytosine bases (5-methylcytosine, 5mC) occurring in vertebrate genomes is usually associated with transcriptional silencing. 5-hydroxylmethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) are the recently discovered modified cytosine bases produced by enzymatic...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Abakir, Abdulkadir, Wheldon, Lee, Johnson, Andrew D., Laurent, Patrick, Ruzov, Alexey
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091899/
https://ncbi.nlm.nih.gov/pubmed/27585398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54416
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