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G protein-coupled receptors: In silico drug discovery in 3D

The application of structure-based in silico methods to drug discovery is still considered a major challenge, especially when the x-ray structure of the target protein is unknown. Such is the case with human G protein-coupled receptors (GPCRs), one of the most important families of drug targets, whe...

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Detalhes bibliográficos
Main Authors: Becker, Oren M., Marantz, Yael, Shacham, Sharon, Inbal, Boaz, Heifetz, Alexander, Kalid, Ori, Bar-Haim, Shay, Warshaviak, Dora, Fichman, Merav, Noiman, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC509175/
https://ncbi.nlm.nih.gov/pubmed/15277683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401862101
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