Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase.

Nitric oxide (NO), constitutively produced by endothelial nitric oxide synthase (eNOS), plays a major role in the regulation of blood pressure and vascular tone. We generated transgenic mice overexpressing bovine eNOS in the vascular wall using murine preproendothelin-1 promoter. In transgenic linea...

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Hauptverfasser: Ohashi, Y, Kawashima, S, Hirata, K i, Yamashita, T, Ishida, T, Inoue, N, Sakoda, T, Kurihara, H, Yazaki, Y, Yokoyama, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC509160/
https://ncbi.nlm.nih.gov/pubmed/9854041
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