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Type 2 iodothyronine deiodinase in rat pituitary tumor cells is inactivated in proteasomes.

The goal of these studies was to define the rate-limiting steps in the inactivation of type 2 iodothyronine deiodinase (D2). We examined the effects of ATP depletion, a lysosomal protease inhibitor, and an inhibitor of actin polymerization on D2 activity in the presence or absence of cycloheximide o...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Steinsapir, J, Harney, J, Larsen, P R
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509140/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835613/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI4672
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