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Evidence for multiple mechanisms of polyclonal T cell activation in murine lupus.

Individuals with systemic autoantibody-mediated diseases such as lupus have polyclonal T and B cell activation. Yet, autoantibody production is restricted to certain autoantigens. The mechanisms underlying this phenomenon remain unclear. We propose three potential mechanisms by which autoreactive he...

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Autors principals: Singh, R R, Hahn, B H, Tsao, B P, Ebling, F M
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC509134/
https://ncbi.nlm.nih.gov/pubmed/9819370
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