Ex vivo reversal of effects of rivaroxaban evaluated using thromboelastometry and thrombin generation assay

BACKGROUND: In major bleeding events, the new direct oral anticoagulants pose a great challenge for physicians. The aim of the study was to test for ex vivo reversal of the direct oral anticoagulant rivaroxaban with various non-specific reversal agents: prothrombin complex concentrate (PCC), activat...

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Bibliographic Details
Published in:Br J Anaesth
Main Authors: Schenk, B., Würtinger, P., Streif, W., Sturm, W., Fries, D., Bachler, M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Cardiovascular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091332/
https://ncbi.nlm.nih.gov/pubmed/27623677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bja/aew259
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