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Reversal of rivaroxaban anticoagulant effect by prothrombin complex concentrates: which dose is sufficient to restore normal thrombin generation?

Rivaroxaban has the most available data to support the use of prothrombin complex concentrates (PCC) as a reversal agent. However, PCC might increase the incidence of thrombotic events by shifting the haemostatic balance towards hypercoagulability. We assessed the in vitro efficacy and safety of thr...

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Detalhes bibliográficos
Publicado no:Thromb J
Main Authors: Giffard-Quillon, Lorine, Desmurs-Clavel, Helene, Grange, Claire, Jourdy, Yohann, Dargaud, Yesim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444267/
https://ncbi.nlm.nih.gov/pubmed/32855623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12959-020-00228-9
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