Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis.

The immunodominant antimitochondrial antibody response in patients with primary biliary cirrhosis (PBC) is directed against the E2 component of the pyruvate dehydrogenase complex (PDC-E2). Based on our earlier observations regarding peripheral blood mononuclear cell (PBMC) T cell epitopes, we reason...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Shimoda, S, Van de Water, J, Ansari, A, Nakamura, M, Ishibashi, H, Coppel, R L, Lake, J, Keeffe, E B, Roche, T E, Gershwin, M E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509133/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI4213
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