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Chronic early life lead (Pb(2+)) exposure alters presynaptic vesicle pools in hippocampal synapses

BACKGROUND: Lead (Pb(2+)) exposure has been shown to impair presynaptic neurotransmitter release in both in vivo and in vitro model systems. The mechanism by which Pb(2+) impairs neurotransmitter release has not been fully elucidated. In previous work, we have shown that Pb(2+) exposure inhibits ves...

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Vydáno v:BMC Pharmacol Toxicol
Hlavní autoři: Guariglia, Sara Rose, Stansfield, Kirstie H., McGlothan, Jennifer, Guilarte, Tomas R.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090882/
https://ncbi.nlm.nih.gov/pubmed/27802838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-016-0098-1
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