Effects of triptolide on hippocampal microglial cells and astrocytes in the APP/PS1 double transgenic mouse model of Alzheimer's disease

The principal pathology of Alzheimer's disease includes neuronal extracellular deposition of amyloid-beta peptides and formation of senile plaques, which in turn induce neuroinflammation in the brain. Triptolide, a natural extract from the vine-like herb Tripterygium wilfordii Hook F, has poten...

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Udgivet i:Neural Regen Res
Main Authors: Li, Jian-ming, Zhang, Yan, Tang, Liang, Chen, Yong-heng, Gao, Qian, Bao, Mei-hua, Xiang, Ju, Lei, De-liang
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2016
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090855/
https://ncbi.nlm.nih.gov/pubmed/27857756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.191224
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