Estrogen upregulates cyclooxygenase-1 gene expression in ovine fetal pulmonary artery endothelium.
Prostacyclin (PGI2) is a key mediator of pulmonary vasodilation in the perinatal period and its synthesis in the pulmonary vasculature increases markedly during late gestation due to enhanced expression of the rate-limiting enzyme cyclooxygenase-1 (COX-1). The hormone estrogen may play a role in COX...
שמור ב:
| הוצא לאור ב: | J Clin Invest |
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| Principais autores: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
1998
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509079/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9649571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2034 |
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