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Quantitative comparison between poly(L-arginine) and poly(L-lysine) at each step of polyplex-based gene transfection using a microinjection technique

Among the well-studied polypeptide-type gene carriers, transfection efficiency is empirically known to be higher for poly(L-arginine) (PR) than poly(L-lysine) (PK). The big difference between PR and PK should be determined at one of the intracellular trafficking steps based on the different charge d...

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Detalles Bibliográficos
Publicado en:Sci Technol Adv Mater
Main Authors: Hashimoto, Tomoko, Kawazu, Takeshi, Nagasaki, Takeshi, Murakami, Akira, Yamaoka, Tetsuji
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090301/
https://ncbi.nlm.nih.gov/pubmed/27877476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1468-6996/13/1/015009
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