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Identification of the critical residues responsible for differential reactivation of the triosephosphate isomerases of two trypanosomes
The reactivation of triosephosphate isomerase (TIM) from unfolded monomers induced by guanidine hydrochloride involves different amino acids of its sequence in different stages of protein refolding. We describe a systematic mutagenesis method to find critical residues for certain physico-chemical pr...
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| Publicado no: | Open Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5090059/ https://ncbi.nlm.nih.gov/pubmed/27733588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160161 |
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