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Determining optimal treatment strategy for diffuse glioma: the emerging role of IDH mutations
The isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) genes mutate frequently in gliomas, and it has become increasingly apparent that IDH mutation status accounts for much of the prognostic information previously rendered by histological grading. Most glioblastomas (90–95%) are IDH-wild type and mos...
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| Publicado en: | Expert Rev Anticancer Ther |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089964/ https://ncbi.nlm.nih.gov/pubmed/25980633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2015.1047351 |
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