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Determining optimal treatment strategy for diffuse glioma: the emerging role of IDH mutations

The isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) genes mutate frequently in gliomas, and it has become increasingly apparent that IDH mutation status accounts for much of the prognostic information previously rendered by histological grading. Most glioblastomas (90–95%) are IDH-wild type and mos...

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Bibliografske podrobnosti
izdano v:Expert Rev Anticancer Ther
Main Authors: Juratli, Tareq A., Cahill, Daniel P., McCutcheon, Ian E.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089964/
https://ncbi.nlm.nih.gov/pubmed/25980633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2015.1047351
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