Reduced binding and phagocytosis of Pneumocystis carinii by alveolar macrophages from persons infected with HIV-1 correlates with mannose receptor downregulation.

The macrophage mannose receptor, a pattern recognition molecule and component of innate immunity, mediates binding and phagocytosis of Pneumocystis carinii and likely represents an important clearance mechanism in the lungs of immunocompetent hosts. The purpose of this study was to examine the abili...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Koziel, H, Eichbaum, Q, Kruskal, B A, Pinkston, P, Rogers, R A, Armstrong, M Y, Richards, F F, Rose, R M, Ezekowitz, R A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508980/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9769325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI560
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