Reduced binding and phagocytosis of Pneumocystis carinii by alveolar macrophages from persons infected with HIV-1 correlates with mannose receptor downregulation.

The macrophage mannose receptor, a pattern recognition molecule and component of innate immunity, mediates binding and phagocytosis of Pneumocystis carinii and likely represents an important clearance mechanism in the lungs of immunocompetent hosts. The purpose of this study was to examine the abili...

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Bibliografiske detaljer
Main Authors: Koziel, H, Eichbaum, Q, Kruskal, B A, Pinkston, P, Rogers, R A, Armstrong, M Y, Richards, F F, Rose, R M, Ezekowitz, R A
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508980/
https://ncbi.nlm.nih.gov/pubmed/9769325
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