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The biology behind B-cell lymphoma 2 as a target in chronic lymphocytic leukemia
B-cell lymphoma 2 (BCL2)-type proteins are key regulators of the intrinsic or mitochondrial pathway for apoptosis. Since escape from apoptosis is one the main ‘hallmarks of cancer’, BCL2 inhibitors have emerged as promising therapeutic agents for diverse lymphoid malignancies, particularly chronic l...
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| Publicado no: | Ther Adv Hematol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089327/ https://ncbi.nlm.nih.gov/pubmed/27904736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620716671313 |
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