Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection.

Human invasive soft-tissue infections caused by group A Streptococcus are associated with significant morbidity and mortality. To investigate the pathogenesis of these serious infections, we characterized the host response to bacterial challenge with an M-type 3 isolate recovered from a patient with...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Ashbaugh, C D, Warren, H B, Carey, V J, Wessels, M R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1998
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508916/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9691092/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI3065
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