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Obesity and diabetes in TNF-alpha receptor- deficient mice.

TNF-alpha may play a role in mediating insulin resistance associated with obesity. This concept is based on studies of obese rodents and humans, and cell culture models. TNF elicits cellular responses via two receptors called p55 and p75. Our purpose was to test the involvement of TNF in glucose hom...

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Published in:J Clin Invest
Main Authors: Schreyer, S A, Chua, S C, LeBoeuf, R C
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508899/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9664082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2849
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