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Specific Delivery of MiRNA for High Efficient Inhibition of Prostate Cancer by RNA Nanotechnology

Both siRNA and miRNA can serve as powerful gene-silencing reagents but their specific delivery to cancer cells in vivo without collateral damage to healthy cells remains challenging. We report here the application of RNA nanotechnology for specific and efficient delivery of anti-miRNA seed-targeting...

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Publicat a:Mol Ther
Autors principals: Binzel, Daniel W, Shu, Yi, Li, Hui, Sun, Meiyan, Zhang, Qunshu, Shu, Dan, Guo, Bin, Guo, Peixuan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088763/
https://ncbi.nlm.nih.gov/pubmed/27125502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.85
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