Specific Delivery of MiRNA for High Efficient Inhibition of Prostate Cancer by RNA Nanotechnology

Both siRNA and miRNA can serve as powerful gene-silencing reagents but their specific delivery to cancer cells in vivo without collateral damage to healthy cells remains challenging. We report here the application of RNA nanotechnology for specific and efficient delivery of anti-miRNA seed-targeting...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Binzel, Daniel W, Shu, Yi, Li, Hui, Sun, Meiyan, Zhang, Qunshu, Shu, Dan, Guo, Bin, Guo, Peixuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088763/
https://ncbi.nlm.nih.gov/pubmed/27125502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.85
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