A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation.

The hydrophilic bile salt ursodeoxycholic acid (UDCA) protects against the membrane-damaging effects associated with hydrophobic bile acids. This study was undertaken to (a) determine if UDCA inhibits apoptosis from deoxycholic acid (DCA), as well as from ethanol, TGF-beta1, Fas ligand, and okadaic...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Rodrigues, C M, Fan, G, Ma, X, Kren, B T, Steer, C J
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1998
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508870/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9637713/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1325
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