Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase.

We tested 42 tetrapeptides for their ability to bind to the rat brain p21ras protein farnesyltransferase as estimated by their ability to compete with p21Ha-ras in a farnesyltransfer assay. Peptides with the highest affinity had the structure Cys-A1-A2-X, where positions A1 and A2 are occupied by al...

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הוצא לאור ב:	Proc Natl Acad Sci U S A
Principais autores:	Reiss, Y, Stradley, S J, Gierasch, L M, Brown, M S, Goldstein, J L
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	National Academy of Sciences 1991
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1992464/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.3.732
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