Assessment of ‘one-step’ versus ‘sequential’ embryo culture conditions through embryonic genome methylation and hydroxymethylation changes

STUDY QUESTION: In comparison to in vivo development, how do different conditions of in vitro culture (‘one step’ versus ‘sequential medium’) impact DNA methylation and hydroxymethylation in preimplantation embryos? SUMMARY ANSWER: Using rabbit as a model, we show that DNA methylation and hydroxymet...

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Detalhes bibliográficos
Publicado no:Hum Reprod
Main Authors: Salvaing, J., Peynot, N., Bedhane, M. N., Veniel, S., Pellier, E., Boulesteix, C., Beaujean, N., Daniel, N., Duranthon, V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088634/
https://ncbi.nlm.nih.gov/pubmed/27664206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dew214
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