Stimulation of bile duct epithelial secretion by glybenclamide in normal and cholestatic rat liver.

Cholestasis is a cardinal complication of liver disease, but most treatments are merely supportive. Here we report that the sulfonylurea glybenclamide potently stimulates bile flow and bicarbonate excretion in the isolated perfused rat liver. Video-microscopic studies of isolated hepatocyte couplets...

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Hlavní autoři: Nathanson, M H, Burgstahler, A D, Mennone, A, Dranoff, J A, Rios-Velez, L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC508857/
https://ncbi.nlm.nih.gov/pubmed/9637700
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