An in vivo multiplexed small molecule screening platform

Phenotype-based small molecule screening is a powerful method to identify regulators of cellular function. However, such screens are generally performed in vitro using conditions that do not necessarily model complex physiological conditions or disease states. Here, we use molecular cell barcoding t...

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Gepubliceerd in:Nat Methods
Hoofdauteurs: Grüner, Barbara M., Schulze, Christopher J., Yang, Dian, Ogasawara, Daisuke, Dix, Melissa M., Rogers, Zoë N., Chuang, Chen-Hua, McFarland, Christopher D., Chiou, Shin-Heng, Brown, J. Mark, Cravatt, Benjamin F., Bogyo, Matthew, Winslow, Monte M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088491/
https://ncbi.nlm.nih.gov/pubmed/27617390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3992
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