Inhibition of mesangial cell proliferation by E2F decoy oligodeoxynucleotide in vitro and in vivo.

The transcription factor E2F coordinately activates several cell cycle-regulatory genes. We attempted to inhibit the proliferation of mesangial cells in vitro and in vivo by inhibiting E2F activity using a 25-bp decoy oligodeoxynucleotide that contained consensus E2F binding site sequence (E2F-decoy...

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Detalhes bibliográficos
Main Authors: Maeshima, Y, Kashihara, N, Yasuda, T, Sugiyama, H, Sekikawa, T, Okamoto, K, Kanao, K, Watanabe, Y, Kanwar, Y S, Makino, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508848/
https://ncbi.nlm.nih.gov/pubmed/9616230
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