Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.

Treatment of C57BL/6 mice with one transfusion of BALB/c spleen cells and anti-CD154 (anti-CD40-ligand) antibody permits BALB/c islet grafts to survive indefinitely and BALB/c skin grafts to survive for approximately 50 d without further intervention. The protocol induces long-term allograft surviva...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Markees, T G, Phillips, N E, Gordon, E J, Noelle, R J, Shultz, L D, Mordes, J P, Greiner, D L, Rossini, A A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508834/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9616216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2703
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