Leukocyte Adhesion Deficiency Type II is a generalized defect of de novo GDP-fucose biosynthesis. Endothelial cell fucosylation is not required for neutrophil rolling on human nonlymphoid endothelium.

Leukocyte Adhesion Deficiency Type II (LAD II) is a recently described syndrome and the two patients with this defect lack fucosylated glycoconjugates. These glycoconjugates include the selectin ligand, sialyl LewisX, and various fucosylated blood group antigens. To date, the molecular anomaly in th...

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Detalhes bibliográficos
Main Authors: Karsan, A, Cornejo, C J, Winn, R K, Schwartz, B R, Way, W, Lannir, N, Gershoni-Baruch, R, Etzioni, A, Ochs, H D, Harlan, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508833/
https://ncbi.nlm.nih.gov/pubmed/9616215
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