Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that epsilon is the isoform involved.

Brief ischemic episodes confer marked protection against myocardial stunning 1-3 d later (late preconditioning [PC] against stunning). The mechanism of this powerful protective effect is poorly understood. Although protein kinase C (PKC) has been implicated in PC against infarction, it is unknown wh...

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Detalhes bibliográficos
Main Authors: Qiu, Y, Ping, P, Tang, X L, Manchikalapudi, S, Rizvi, A, Zhang, J, Takano, H, Wu, W J, Teschner, S, Bolli, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508806/
https://ncbi.nlm.nih.gov/pubmed/9593774
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