Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase Activity

Posttranslational modifications (PTMs) of proteins play a crucial role in regulating protein-protein interactions, enzyme activity, subcellular localization, and stability of the protein. SET domain, bifurcated 1 (SETDB1) is a histone methyltransferase that regulates the methylation of histone H3 on...

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Pubblicato in:PLoS One
Autori principali: Ishimoto, Kenji, Kawamata, Natsuko, Uchihara, Yoshie, Okubo, Moeka, Fujimoto, Reiko, Gotoh, Eiko, Kakinouchi, Keisuke, Mizohata, Eiichi, Hino, Nobumasa, Okada, Yoshiaki, Mochizuki, Yasuhiro, Tanaka, Toshiya, Hamakubo, Takao, Sakai, Juro, Kodama, Tatsuhiko, Inoue, Tsuyoshi, Tachibana, Keisuke, Doi, Takefumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087952/
https://ncbi.nlm.nih.gov/pubmed/27798683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165766
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