LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria.

LPS-binding protein (LBP) recognizes bacterial LPS and transfers it to CD14, thereby enhancing host cell stimulation, eventually resulting in pathogenic states such as septic shock. Recently, LBP also was shown to detoxify LPS by transferring LPS into HDL particles in vitro. Thus, the predominant in...

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Bibliographische Detailangaben
Hauptverfasser: Lamping, N, Dettmer, R, Schröder, N W, Pfeil, D, Hallatschek, W, Burger, R, Schumann, R R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508794/
https://ncbi.nlm.nih.gov/pubmed/9593762
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