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Rolipram Protects Mice from Gram-negative Bacterium Escherichia coli-induced Inflammation and Septic Shock

Sepsis is typically triggered by an overwhelming systemic inflammatory response to pathogens, and may lead to severe organ dysfunction and/or death. Sepsis consequently has a high mortality rate and a high rate of complications for survivors, despite modern medical advances. Therefore, drug identifi...

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Publicat a:Sci Rep
Autors principals: Lu, Xiaying, Wang, Juan, Chen, Xiaohuan, Jiang, Yong, Pan, Zhixing K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957694/
https://ncbi.nlm.nih.gov/pubmed/31932743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56899-6
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