Application of High-Throughput Next-Generation Sequencing for HLA Typing on Buccal Extracted DNA: Results from over 10,000 Donor Recruitment Samples

BACKGROUND: Unambiguous HLA typing is important in hematopoietic stem cell transplantation (HSCT), HLA disease association studies, and solid organ transplantation. However, current molecular typing methods only interrogate the antigen recognition site (ARS) of HLA genes, resulting in many cis-trans...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Yin, Yuxin, Lan, James H., Nguyen, David, Valenzuela, Nicole, Takemura, Ping, Bolon, Yung-Tsi, Springer, Brianna, Saito, Katsuyuki, Zheng, Ying, Hague, Tim, Pasztor, Agnes, Horvath, Gyorgy, Rigo, Krisztina, Reed, Elaine F., Zhang, Qiuheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087893/
https://ncbi.nlm.nih.gov/pubmed/27798706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165810
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