Statin action enriches HDL3 in polyunsaturated phospholipids and plasmalogens and reduces LDL-derived phospholipid hydroperoxides in atherogenic mixed dyslipidemia

Atherogenic mixed dyslipidemia associates with oxidative stress and defective HDL antioxidative function in metabolic syndrome (MetS). The impact of statin treatment on the capacity of HDL to inactivate LDL-derived, redox-active phospholipid hydroperoxides (PCOOHs) in MetS is indeterminate. Insulin-...

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Vydáno v:J Lipid Res
Hlavní autoři: Orsoni, Alexina, Thérond, Patrice, Tan, Ricardo, Giral, Philippe, Robillard, Paul, Kontush, Anatol, Meikle, Peter J., Chapman, M. John
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2016
Témata:
Patient-Oriented and Epidemiological Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087874/
https://ncbi.nlm.nih.gov/pubmed/27581680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P068585
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