Statin action enriches HDL3 in polyunsaturated phospholipids and plasmalogens and reduces LDL-derived phospholipid hydroperoxides in atherogenic mixed dyslipidemia

Atherogenic mixed dyslipidemia associates with oxidative stress and defective HDL antioxidative function in metabolic syndrome (MetS). The impact of statin treatment on the capacity of HDL to inactivate LDL-derived, redox-active phospholipid hydroperoxides (PCOOHs) in MetS is indeterminate. Insulin-...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Orsoni, Alexina, Thérond, Patrice, Tan, Ricardo, Giral, Philippe, Robillard, Paul, Kontush, Anatol, Meikle, Peter J., Chapman, M. John
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Patient-Oriented and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087874/
https://ncbi.nlm.nih.gov/pubmed/27581680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P068585
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