Statin action enriches HDL3 in polyunsaturated phospholipids and plasmalogens and reduces LDL-derived phospholipid hydroperoxides in atherogenic mixed dyslipidemia

Atherogenic mixed dyslipidemia associates with oxidative stress and defective HDL antioxidative function in metabolic syndrome (MetS). The impact of statin treatment on the capacity of HDL to inactivate LDL-derived, redox-active phospholipid hydroperoxides (PCOOHs) in MetS is indeterminate. Insulin-...

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Publicat a:J Lipid Res
Autors principals: Orsoni, Alexina, Thérond, Patrice, Tan, Ricardo, Giral, Philippe, Robillard, Paul, Kontush, Anatol, Meikle, Peter J., Chapman, M. John
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2016
Matèries:
Patient-Oriented and Epidemiological Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087874/
https://ncbi.nlm.nih.gov/pubmed/27581680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P068585
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