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The adhesion molecule PECAM-1 enhances the TGFβ-mediated inhibition of T cell function
Transforming growth factor-β (TGF-β) is an immunosuppressive cytokine that inhibits the pro-inflammatory functions of T cells, and it is a major factor in abrogating T cell activity against tumors. Canonical signaling results in the activation of Smad proteins, transcription factors that regulate ta...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Sci Signal |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087802/ https://ncbi.nlm.nih.gov/pubmed/26956486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aad1242 |
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