Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run

Mammalian KIF3AB is an N-terminal processive kinesin-2 that is best known for its roles in intracellular transport. There has been significant interest in KIF3AB to define the key principles that underlie its processivity but also to define the mechanistic basis of its sensitivity to force. In this...

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Udgivet i:J Biol Chem
Main Authors: Albracht, Clayton D., Guzik-Lendrum, Stephanie, Rayment, Ivan, Gilbert, Susan P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087741/
https://ncbi.nlm.nih.gov/pubmed/27637334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752196
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