Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules

Mammalian KIF3AC is classified as a heterotrimeric kinesin-2 that is best known for organelle transport in neurons, yet in vitro studies to characterize its single molecule behavior are lacking. The results presented show that a KIF3AC motor that includes the native helix α7 sequence for coiled-coil...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Guzik-Lendrum, Stephanie, Rank, Katherine C., Bensel, Brandon M., Taylor, Keenan C., Rayment, Ivan, Gilbert, Susan P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Molecular Machines, Motors, and Nanoscale Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601047/
https://ncbi.nlm.nih.gov/pubmed/26445448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.004
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