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Functional Analysis of γ-Tubulin Complex Proteins Indicates Specific Lateral Association via Their N-terminal Domains

Microtubules are nucleated from multiprotein complexes containing γ-tubulin and associated γ-tubulin complex proteins (GCPs). Small complexes (γTuSCs) comprise two molecules of γ-tubulin bound to the C-terminal domains of GCP2 and GCP3. γTuSCs associate laterally into helical structures, providing a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Farache, Dorian, Jauneau, Alain, Chemin, Cécile, Chartrain, Marine, Rémy, Marie-Hélène, Merdes, Andreas, Haren, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087730/
https://ncbi.nlm.nih.gov/pubmed/27660388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744862
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