Functional Analysis of γ-Tubulin Complex Proteins Indicates Specific Lateral Association via Their N-terminal Domains

Microtubules are nucleated from multiprotein complexes containing γ-tubulin and associated γ-tubulin complex proteins (GCPs). Small complexes (γTuSCs) comprise two molecules of γ-tubulin bound to the C-terminal domains of GCP2 and GCP3. γTuSCs associate laterally into helical structures, providing a...

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Vydáno v:J Biol Chem
Hlavní autoři: Farache, Dorian, Jauneau, Alain, Chemin, Cécile, Chartrain, Marine, Rémy, Marie-Hélène, Merdes, Andreas, Haren, Laurence
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087730/
https://ncbi.nlm.nih.gov/pubmed/27660388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744862
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