The Rab3A-22A Chimera Prevents Sperm Exocytosis by Stabilizing Open Fusion Pores

At the final stage of exocytotis, a fusion pore opens between the plasma and a secretory vesicle membranes; typically, when the pore dilates the vesicle releases its cargo. Sperm contain a large dense-core secretory granule (the acrosome) whose contents are secreted by regulated exocytosis at fertil...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Quevedo, María F., Lucchesi, Ornella, Bustos, Matías A., Pocognoni, Cristian A., De la Iglesia, Paola X., Tomes, Claudia N.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087729/
https://ncbi.nlm.nih.gov/pubmed/27613869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729954
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