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Rab27 and Rab3 sequentially regulate human sperm dense-core granule exocytosis

Two so-called “secretory Rabs,” Rab3 and Rab27, regulate late steps during dense-core vesicle exocytosis in neuroendocrine cells. Sperm contain a single large dense-core granule that is released by regulated exocytosis (termed the acrosome reaction) during fertilization or on exposure to inducers in...

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Detalhes bibliográficos
Main Authors: Bustos, Matías A., Lucchesi, Ornella, Ruete, María C., Mayorga, Luis S., Tomes, Claudia N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409754/
https://ncbi.nlm.nih.gov/pubmed/22753498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121173109
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