Induction of Glucocorticoid-induced Leucine Zipper (GILZ) Contributes to Anti-inflammatory Effects of the Natural Product Curcumin in Macrophages

GILZ (glucocorticoid-induced leucine zipper) is inducible by glucocorticoids and plays a key role in their mode of action. GILZ attenuates inflammation mainly by inhibition of NF-κB and mitogen-activated protein kinase activation but does not seem to be involved in the severe side effects observed a...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Hoppstädter, Jessica, Hachenthal, Nina, Valbuena-Perez, Jenny Vanessa, Lampe, Sebastian, Astanina, Ksenia, Kunze, Michael M., Bruscoli, Stefano, Riccardi, Carlo, Schmid, Tobias, Diesel, Britta, Kiemer, Alexandra K.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087716/
https://ncbi.nlm.nih.gov/pubmed/27629417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733253
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