Virulence of catalase-deficient aspergillus nidulans in p47(phox)-/- mice. Implications for fungal pathogenicity and host defense in chronic granulomatous disease.

Chronic granulomatous disease (CGD) is a rare genetic disorder in which phagocytes fail to produce superoxide because of defects in one of several components of the NADPH oxidase complex. As a result, patients develop recurrent life-threatening bacterial and fungal infections. The organisms to which...

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Publié dans:	J Clin Invest
Auteurs principaux:	Chang, Y C, Segal, B H, Holland, S M, Miller, G F, Kwon-Chung, K J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1998
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576747/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2301
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